Intracellular markers for ions

Principle :

Variation of emission or excitation yield of fluorophores forming specific complexes with ions.

 

Examples :

Calcium: FURA-2, Fura-5, Fura Red, Indo-1, Calcium Green,..

Protons: CECF, SNARF-6, SNAFL-1,..

Sodium: BFI, FCRYP-2,..

Potassium: PBFI

Magnesium: Mag-Fura-2

Chloride: SPQ

 

Application :

Often used as a „pro drug“ e.g. an ester being hydrolyzed by cell lipases