T-Cell-Epitopes

 

Structure:

 

        - small linear peptide 8-12 Aa

        - amphipathic alpha-helix

        - extended conformation

        - -Gly(charged)-hydrophobic-hydrophobic-Gly(charged)-

        - hyper-variable

        - direct response to peptide !

 

Sequence from LDH :

 

S T V K E Q L I E K L I E D D E N S Q C .... = Aa 1 - 20

E K L I E D D E N S Q C .... = Aa 9 - 20